13 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
IRIS might ... should be based on clinical ... Demyelinating disease ... caused by the JC ... opportunistic #InfectiousDiseases
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... noncompliance • Clinical ... initiation Clinical ... pleural effusions, CNS
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... and Management Summary ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Drugs, Unknown cause ... management #treatment #summary
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management Summary ... • Most common cause ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Diagnosis: • CBC
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Diagnosis Framework Disease ... Pneumonia: • 3 syndromes ... angioinvasive disease ... Lymphadenopathy, CNS ... differential #diagnosis #infectiousdiseases
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
- OnePager Summary ... life-threatening diseases ... Inflammatory eye disease ... coagulopathy) • CBC ... Goodpasture's cause
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... salivary ducts Clinical ... nervous system (CNS ... • 8%-27% for CNS
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management Summary ... Prevalence: 1-2 cases ... Pathophysiology ... Clinical Manifestations ... Baclofen • Severe Disease