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lupus differential druginduced syndrome erythematosus summary systemic treatment vasculitis activation anesthesia anesthesiology behcet checklist cico classification comparison difficult dil disease
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Management Summary ... • Immunologic Workup ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... • Immunologic Workup ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
SLE High risk ... #DrugInduced #SLE ... #pharmacology # ... #differential #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: Inflammatory eye ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Autoimmune diseases: SLE ... immune deficiency, Drugs ... #management #treatment ... #summary #rheumatology
Can’t Intubate, Can’t Oxygenate (CICO) - Guidelines for Crises in Anaesthesia This is the last resort when
neuromuscular blocking drug ... Access – FoNA (see ... the laryngeal anatomy ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Arthralgias • Eye ... Eye -> retinopathy ... vasculitis, and SLE ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... ) • Sepsis • Drug-induced ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... : • Dry eyes • ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... atherosclerotic disease, drug ... Arthralgias • Eye ... viral infection, drug ... #Rheumatology
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