50 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Diagnosis Framework ... Infectious Knee ... #diagnosis #msk ... #physicalexam
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Diagnosis Congenital ... Wiskott-Aldrich syndrome ... deficiency Infections ... Cytomegalovirus • Epstein-Barr ... #Diagnosis #Hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... response preceding infection ... Clinical Features ... Diagnosis: • ... #Syndrome #diagnosis
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Chemotherapy • Infectious ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... Peripheral #Neuropathy #differential ... #diagnosis #causes
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... immunodeficiency virus (HIV ... transplantation CLINICAL ... • Onset: few days ... #Syndrome #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Diagnosis Algorithm ... Quinidine • HIT ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... #Causes #Hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Diagnosis Algorithm ... Antineoplastic Viral Infection ... • Epstein-Barr ... Childhood viruses • HIV ... #Causes #Hematology
Causes of Myocarditis
Infectious Etiologies:
 • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
of Myocarditis Infectious ... herpesvirus 6, Epstein—Barr ... Hepatitis C virus, HIV ... #Myocarditis #differential ... #diagnosis #cardiology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Diagnosis Algorithm ... • Malignancy Infectious ... Tuberculosis • Epstein-Barr ... Hepatitis • HIV ... Chronic Fatigue Syndrome
Infectious Causes of Adrenal Insufficiency
Anatomical distribution of vessels to the adrenal makes the gland prone to
Waterhouse-Friderichsen syndrome ... canimorsus • Virus: HIV ... Cytomegalovirus, Epstein-Barr ... Insufficiency #AI #differential ... #diagnosis #endocrinology