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Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... than females Guillain-Barre ... bulbar muscles Guillain-Barre ... • Areflexia Guillain-Barre ... #Barre #Syndrome
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Inflammatory/AI ... : CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Causes of Pediatric Constipation - Differential Diagnosis Algorithm
Dietary / Functional:
 • Insufficient Volume / Bulk
Neurologic:
 •
Causes of Pediatric ... - Differential Diagnosis ... Congenita • Guillain-Barré ... Syndrome • Muscular ... #Peds #Pediatrics
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Poliomyelitis, Guillain-Barre ... Shellfish poisoning, Meds ... #differential #diagnosis ... #neurology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
Reflexes: • Knee ... • Cauda Equina Syndrome ... Commonly caused ... #Myotomes #diagnosis ... #neurology #sensory
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
Upper Extremity Dermatomes ... Carpal Tunnel Syndrome ... #Myotomes #diagnosis ... #neurology #sensory ... #motor #arm #physicalexam
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... • Onset: few days ... #Barre #Syndrome ... #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
(CES) is usually ... - Emergency Causes ... Tethered cord • Guillain-Barre ... region (S2-S4 dermatomes ... #causes #neurology
Pediatric Constipation - Differential Diagnosis Algorithm
Dietary/Functional
 • lnsufficient Volume / Bulk
Neurologic
 • Hirschsprung's Disease
 • Imperforate
- Differential Diagnosis ... Congenita • Guillan-Barré ... Syndrome #Constipation ... #Algorithm #Causes ... #Peds