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hematology apml differentiation disease encephalopathy hemophagocytic hlh icu intensivecare kawasaki leukostasis lymphohistiocytosis lysis neurology oncology pediatrics pics post posterior pres
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
systemic acute febrile ... immunoglobulin reduces the risk ... Kawasaki #Disease #Features ... #Signs #Symptoms ... #Diagnosis #Peds
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... Treatment: - If febrile ... worrisome EKG features ... #TLS #diagnosis ... #management #hematology
Post-Intensive Care Syndrome (PICS) Symptoms of PICS: - Physical Domain: Generalized weakness, Fatigue, Difficulty walking - Cognitive
Post-Intensive Care Syndrome ... (PICS) Symptoms ... Depression COMMON RISK ... #PICS #diagnosis ... #management #criticalcare
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Rare: DAH, acute febrile ... : >3 symptoms, or ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... HLH signs and symptoms ... acute or subacute febrile ... • Supportive measures ... #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
factor PRES Diagnosis ... Neurological symptoms ... Risk factors 3. ... Seizures: Treat with AEDs ... #diagnosis #management
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