14 results
Nystagmus from Wernicke’s Encephalopathy - Magnetic resonance imaging of the brain showed T2 hyperintensities involving the
Magnetic resonance imaging ... Clinical #Radiology #Neuro ... MRI #Thalamus #NEJM
Creutzfeldt-Jakob Disease - Magnetic resonance imaging (MRI) revealed hyperintensity of the cortical gyri of the frontal
Magnetic resonance imaging ... diffusion-weighted imaging ... #Clinical #Neuro ... CreutzfeldJakob #NEJM
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Disease Motor Neuron ... • Progressive muscular ... Neuropathy • Spinal Muscular ... Polymyositis • Duchenne Muscular ... Dystrophy • Statin
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
Tearing/sharp/stabbing ... murmur • Focal neuro ... diagnosis #management #vascular
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (Dermato-neuro ... Fanconi, crystal-storing ... Hypergammaglobulinemic macular ... disease (Subcorneal pustular ... (Thrombosis in vascular
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Upper Motor Neuron ... toxins: Steroids, Statins ... myositis • Genetic: Muscular ... myopathies, the muscular
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
• GI bleeding Neuro ... activity of factor X, vascular ... Echocardiogram with Doppler imaging ... • Diagnostic imaging ... Immunohistochemical staining
Central Pontine Myelinolysis - Magnetic resonance imaging of the brain revealed a central area of high
Magnetic resonance imaging ... Clinical #Radiology #Neuro ... Syndrome #ODS #NEJM
Cerebral Cavernous Malformations - Magnetic resonance imaging of the brain revealed numerous lesions consistent with cerebral
Magnetic resonance imaging ... Clinical #Radiology #Neuro ... FamilialCerebralCavernousMalformationSyndrome #NEJM
Macular Hole from a Laser Pointer- Funduscopic examination of the left eye revealed a large macular
Macular Hole from ... revealed a large macular ... full-thickness macular ... autofluorescence imaging ... ophthalmology #NEJM