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oncology hepatology rheumatology aclf activation acute amiodarone anemia aplastic apml blood calcium chronic cirrhosis cppd deposition differentiation disease failure gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Brain Failure Lung ... Coagulation Failure Infections ... Hepatitis (AAH) Drug-Induced ... #diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... skin necrosis (at injection ... #HIT #Heparin #Induced ... #Management #Treatment ... #Hematology #HemeOnc
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
inflammatory cytokines induced ... kidneys, liver, lung ... day 2 + 3 BIDMC Infectious ... #STSS #treatment ... #management #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... endothelial damage • Induce ... : Infection (sepsis ... organ dysfuxtion, ICU ... #management #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... • Platypnea - Dyspnea ... #diagnosis #management ... #treatment #hepatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... Sepsis • Drug-induced ... #Diagnosis #Management ... #Hematology #Rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Penicillamine induced ... myasthenia Diagnosis ... : - Bedside: ice ... precipitated by: Drugs, infection ... #management #neurology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... Dyspnea 3. ... failure - Infectious ... #management #Toxicology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Idiopathic • Infections ... cells is much reduced ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Significance (ICUS ... • Parvovirus infection ... unclassifiable: Reduced ... #diagnosis #hematology
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