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diagnosis oncology hepatology rheumatology aclf activation acute amiodarone anemia aplastic apml blood calcium chronic cirrhosis cppd deposition differentiation disease failure
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Brain Failure Lung ... Coagulation Failure Infections ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... skin necrosis (at injection ... > MICU, ♀, ↑Age ... #HIT #Heparin #Induced ... #Treatment #Hematology
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
inflammatory cytokines induced ... kidneys, liver, lung ... day 2 + 3 BIDMC Infectious ... #STSS #treatment ... #management #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
endothelial damage • Induce ... Differential Diagnosis: Infection ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... Sepsis • Drug-induced ... #Diagnosis #Management ... #Hematology #Rheumatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... • Platypnea - Dyspnea ... on radioactive lung ... #treatment #hepatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... Penicillamine induced ... : - Bedside: ice ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Idiopathic • Infections ... cells is much reduced ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... Dyspnea 3. ... failure - Infectious ... Pulmonary #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Significance (ICUS ... • Parvovirus infection ... unclassifiable: Reduced ... #diagnosis #hematology
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