9 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Jcortesizaguirr #Abnormal ... #differential #hematology ... #coagulation
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTT, Normal PT ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... Causes include : ... amyloidosis #Abnormal ... #differential #hematology ... #coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Destruction • Abnormal ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... Subcutaneous dissecting hematoma ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... the PT remains prolonged ... intravascular coagulation ... discern these causes ... Differential #Diagnosis #Hematology
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
ecchymosis) is caused ... are typical of coagulation ... factor deficiencies ... Excessive bruising & prolonged ... Measurement of coagulation
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Differential Diagnosis Algorithm ... fatigue (e.g. prolonged ... Vaginal laceration / hematoma ... succenturiate lobe • Abnormal
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... deficiency - Abnormal ... Complete blood count coagulation ... #Causes #dermatology