25 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... (INR) - Bleeding ... (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... #coagulation #disorders
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... protein C and S Pathophysiology ... Fibrinogen: ↓ • PT ... Treat primary cause ... #diagnosis #causes
Coagulation Protein Tests (PT and PTT)

#Coagulation #Tests #PTT #algorithm #differential #pathophysiology
Coagulation Protein ... Tests (PT and PTT ... ) #Coagulation ... #Tests #PTT #algorithm ... #differential #pathophysiology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Congenital intrinsic coagulation ... Pre-analytical cause ... intravascular coagulation ... aPTT #Prolonged #Causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... • Bleeding gums ... inhibitor of a coagulation ... intravascular coagulation ... discern these causes
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... Causes include : ... Pre-analytical cause ... differential #hematology #coagulation
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... Qualitative • Coagulation ... vs Acquired #Bleeding ... #pathophysiology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... normal in mild cases ... ) • PT/INR & von ... Treatment - Acute Bleeding ... serious or moderate bleeding
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
ecchymosis) is caused ... are typical of coagulation ... factor deficiencies ... to be normal, PT ... Measurement of coagulation