13 results
Rachitic Rosary of Rickets on Physical Exam

Bead-like prominences of bone are seen at the costochondral joints.
prominences of bone ... PhysicalExam #clinical #video ... #chest #Ribs #VitaminD ... #deficiency #endocrinology
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
Vitamin D
chiefly by hormones vitamin ... Vitamin D enters ... and stimulating bone ... #Pathophysiology ... #Endocrinology
Tweetorial - How does diabetes mellitus (DM) lead to an increased risk of infection? 

By Dr.
Tony Breu @tony_breu ... #DiabetesMellitus ... Risk #Tweetorial #Endocrinology ... #DM #Pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
PTH, ↑Calcium, ↑Vitamin ... PTH, ↓→Calcium, ↓Vitamin ... easily/weakness, Bone ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
C Deficiency) - ... Mucous membranes • Bone ... C deficiency can ... weeks #Scurvy #Pathophysiology ... #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... Symptoms: • GH deficiency ... #FeedbackLoop #endocrinology ... #pathophysiology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
active form of Vitamin ... - Vitamin B12 ... B12 deficiency. ... anemia includes bone ... #Pathophysiology
Thyroid Function Pathway 

Hypothyroidism is a very common condition! Here's a repost of the pathway that
pathway that is deficient ... T4 is low, the body ... Thyroid #Pathway #Pathophysiology ... #Endocrinology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
: Inhibitor of bone ... hypothyroidism • Zinc deficiency ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... collection with EDTA Pathophysiology
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
ALP) • Lack of bone ... ) • Abnormal Vitamin ... of synthesis or vitamin ... D receptor => Bone ... #Osteomalacia #pathophysiology