10 results
Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based tests:
 • FIT: 79% sensitivity, 94% specificity for CRC
Colorectal Cancer Screening ... tests: • FIT: ... for CRC, Poor sensitivity ... Cancer #colon #Screening ... #Testing
ACA Colorectal Cancer Screening Guidelines

When to Screen?
When to Stop?
Family History

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based
Colorectal Cancer Screening ... Colorectal Cancer Screening ... for CRC, Poor sensitivity ... Cancer #colon #Screening ... #Testing #Indications
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
and first-level screening ... test - High sensitivity ... and specificity ... and specificity ... Celiac #Disease #Testing
What is Fecal Occult Blood Testing (FOBT)
 • Screening for colorectal cancer in average risk population
immunochemical test ... indications other than CRC ... to unnecessary testing ... #OccultBlood #Testing ... #FOBT #Guaiac #FalsePositives
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
- CCP antibody testing ... has higher specificity ... but lower sensitivity ... Screening Tests ... Screening Tests
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - Algorithm ... Step 1) Screening ... have almost 100% specificity ... for AI (but low sensitivity ... require Cosyntropin testing
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
Diagnostic algorithm ... hypercalcemia rests ... value of 0.0115, sensitivity ... ) was 0.80 and specificity ... Thus, further testing
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... 96% • Higher specificity ... the use of this test ... #FalsePositives
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Sensitivity (rule ... out – screening ... Specificity (rule ... FN) Higher specificity ... PPV Higher sensitivity
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
Disease - Diagnosis Algorithm ... IgA TTG has high sensitivity ... and specificity ... pts need further testing ... -A negative test