103 results
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Malabsorption, Phosphate ... losses: FGF23, PTH, Fanconi ... causes #nephrology #phosphate
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Appropriately Low Kidney Phosphate ... Diarrhea, Antacids, Phosphate ... Inappropriately High Kidney Phosphate ... • N or ↓FGF23: Fanconi
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Fractional Excretion of Phosphate ... or Low FGF-23: Fanconi ... Framework #Workup #phosphate
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Tubular Defects Fanconi ... Liddle #Syndrome #Fanconi
Phosphate Electrolyte Repletion
Oral: Neutra-Phos, Neutra-Phos-K, K-Phos Neutral (Na and K Phos)
Intravenous: Potassium Phosphate, Sodium Phosphate

Satya Patel
Phosphate Electrolyte ... Intravenous: Potassium Phosphate ... , Sodium Phosphate ... SatyaPatelMD #Phosphate
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... hydrolysis of organic phosphate ... growth) Alkaline phosphatase ... #Alkaline #Phosphatase
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... CKD will require phosphate ... effectively excrete phosphate ... based on serum phosphate ... aluminum-based phosphate
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
heparin Acute Phosphate ... Exogenous: Excessive phosphate ... intake, Phosphate ... Increased Renal Phosphate ... Framework #Workup #phosphate
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
: Ifosfamide - Fanconi ... , Ifosfamide - Fanconi ... BRAF inhibitors- fanconi
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Is Low Alkaline Phosphatase ... • Pyridoxal 5' phosphate ... of Low Alkaline Phosphatase ... Low #Alkaline #Phosphatase