1356 results
Hypophosphatemia Diagnostic Algorithm
- GI Losses
- Redistribution
- 1° HPT
- 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
Hereditary, TIO, Fanconi ... Syndrome, Diamox ... Hypophosphatemia #phosphorus
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Shift: Refeeding Syndrome ... Tumor Genesis Syndrome ... • N or ↓FGF23: Fanconi ... Syndrome, (MM, ... Algorithm #nephrology #phosphorus
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
absorption (Antacids, Phosphorus ... alkalosis, Hungry bone syndrome ... Tumor genesis syndrome ... or Low FGF-23: Fanconi ... syndrome, CA Inh
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Tubular Defects Fanconi ... Syndrome: Proximal ... tubule Bartter Syndrome ... Henle Gitelman Syndrome ... #Fanconi #Bartter
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... Pancytopenia Fanconi ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
: Ifosfamide - Fanconi ... syndrome, Imatinib ... , Ifosfamide - Fanconi ... syndrome, Cetuximab ... BRAF inhibitors- fanconi
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
in Calcium and Phosphorus ... tubular reabsorption Phosphorus ... parathormone #Calcium #Phosphorus
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
of Tumor Lysis Syndrome ... excretion) • Phosphorus ... #TumorLysis #Syndrome
Ashkenazi Jewish Genetic Screening Algorithm
 • Bloom syndrome
 • Canavan disease
 • Familial dysautonomia
 • Fanconi
Algorithm • Bloom syndrome ... dysautonomia • Fanconi ... 1A • Joubert syndrome ... type 1B • Usher syndrome ... type 1F • Usher syndrome
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
), Hungry bone syndrome ... losses: FGF23, PTH, Fanconi