11 results
Therapy for AL Amyloidosis 2019 
 - Antibodies (Plasma cells) 
 - Proteasome Inhibitors 
 -
Antibodies (Plasma cells ... Medications #Therapies #Pharmacology ... #Management #Classes
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
depolarization in fast AP cells ... depolarization in slow AP cells ... depolarization in slow AP cells ... Classification #Classes ... #cardiology #pharmacology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... release from mast cells ... Edema #Medication #Causes ... #Differential #Pharmacology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Microglial cells ... - Causes progressive ... Muscle twitching (fasciculations ... BULBAR: Tongue fasciculations ... Escorial criteria uses
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... increases out of cells ... ++ influx into cells ... Antiarrhythmics #Pharmacology ... Classification #Classes
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
++ influx into cells ... Vaughan #Williams #Pharmacology ... Classification #Classes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , B cells, and plasma ... cells around salivary ... Xerostomia • Dental caries ... lubricants • Pharmacologic
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
CD4 count <150 cells ... histoplasmosis (>10 cases ... CD4 count ≥150 cells ... CD4 count <150 cells ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS
Preventing Chronic Microsporidiosis:
 • Because chronic microsporidiosis occurs
CD4 count >100 cells ... Gastrointestinal Infections Caused ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS
Pre-Exposure Prevention of VZV
CD4 count ≥200 cells ... Uncomplicated Cases ... infections #HIVAIDS #pharmacology