13 results
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... various inflammatory cells ... periumbilical region), nausea ... #HSP #IgA #Vasculitis ... Diagnosis #Signs #Symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Viral replication causes ... vascular endothelial cells ... Diagnosis #Signs #Symptoms ... #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... hair follicles -> causes ... removal of these cells ... Livedo Reticularis, Vasculitis ... diagnosis #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... Multinucleated giant cells ... • Progressive symptoms ... tract, and often causes
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... Muscle twitching (fasciculations ... BULBAR: Tongue fasciculations ... Common Symptoms ... Escorial criteria uses
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... -> AML: Blast crises ... Leukemia #Hematology #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... number of CD34+ cells ... number of CD34+ cells ... • Improve the symptoms ... Aplastic #Anemia #oncology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
the mastoid air cells ... and mastoid air cells ... hearing loss, nausea ... pathophysiology #signs #symptoms ... #diagnosis #otology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... of about three cases ... ingestion • B symptoms ... Lymphoma (90-95% of cases ... classification #hematology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... skin that are caused ... Out Secondary Causes ... diagnosis #hematology #oncology