738 results
diagnosis differential algorithm management clinical cardiology hematology radiology neurology treatment nephrology dermatology pulmonary rheumatology endocrinology pathophysiology hepatology table pediatrics classification
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... dysfunction, ↑ Ferritin ... • Autoimmune diseases ... Adult-onset Still disease ... Drugs, Unknown cause
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Hyperferritinemia Pearl: Diseases ... HLH 2. ... Still's disease ... histoplasmosis #Ferritin
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
Causes of Hyperferritinemia ... > 1000 Ferritin ... Ferritin > 1000 ... HLH or Adult Onset ... In adults, HLH is
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH ... lab findings in HLH ... : ↑↑ ferritin, Anemia ... consistent with HLH ... cell lines) • ↑ ferritin
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... age, however the disease ... / Diagnosis: HLH ... cell activity • Ferritin ... If no response HLH
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... cytokines Common causes ... Rare causes: ... , IgG4-related disease ... Differential #Diagnosis #Causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... highly inflammatory disease ... of underlying disease ... hypersensitivity syndromes • HLH ... dehydrogenase • ↑ Ferritin
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Globin Synthesis Ferritin ... Deficiency (Eg Causes ... Dietary Deficiency) Ferritin ... Inflammation Ferritin
Uveitis - Definition, Causes and SUN Classification Inflammation of the iris, ciliary body, vitreous, retina and/or choroid Incidence
- Definition, Causes ... inhabitants 3rd leading cause ... retinal ischemia Causes ... Inflammatory : HLA ... TerrierBen #Uveitis #Causes
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
→ Inflammation causes ... Diagnosis: Ferritin ... absolute ID) OR Ferritin ... endpoint of all-cause
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