160 results
diagnosis differential algorithm causes management hemolytic rheumatology workup oncology clinical hepatology treatment dermatology disease pathophysiology hemolysis deficiency signs symptoms sicklecell
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH ... lab findings in HLH ... : ↑↑ ferritin, Anemia ... cell lines) • ↑ ferritin ... Lymphohistiocytosis #diagnosis #hematology
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
> 1000 Ferritin ... HLH or Adult Onset ... Hematologic Malignancy ... Sideroblastic anemia ... In adults, HLH is
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... with leukopenia, anemia ... dehydrogenase • ↑ Ferritin ... Diagnosis #Management #Hematology
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
HLH 2. ... histoplasmosis #Ferritin ... Differential #Diagnosis #Hematology
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Saturation, ↓ Ferritin ... Anemia of chronic ... Saturation, ↑-nl Ferritin ... Saturation, ↑-nl Ferritin ... #differential #hematology
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency Anemia ... synthesis • Ferritin ... Iron #Deficiency #Anemia ... #IDA #ferritin ... Fe #diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Globin Synthesis Ferritin ... TlBC > 18% • Anemia ... #Microcytic #Anemia ... Algorithm #Causes #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... Algorithm Labs: Ferritin ... Iron #Deficiency #Anemia ... Diagnosis #Algorithm #ferritin ... #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... erythematosus • HLH ... Differential #Diagnosis #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... MCHC, Serum Iron, Ferritin ... • Anemia of Chronic ... Non-lmmune #Anemia ... Algorithm #Causes #Hematology
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