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diagnosis management algorithm differential checklist hematology pocus anesthesia anesthesiology treatment rheumatology signs intraoperative symptoms pathophysiology video causes criteria psychiatry syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH ... ) Clinical Features ... lab findings in HLH ... : ↑↑ ferritin, Anemia ... cell lines) • ↑ ferritin
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
HLH 2. ... histoplasmosis #Ferritin
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
Differential Diagnosis Ferritin ... > 1000 Ferritin ... hepcidin prevents ferritin ... HLH or Adult Onset ... In adults, HLH is
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Screen for HLH ... HLH syndrome 5. ... #Pancytopenia #Workup
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... accumulation of clinical ... Assessment • Clinical ... dysfunction, ↑ Ferritin ... • Familial HLH
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... : Overwhelming clinical ... / Diagnosis: HLH ... cell activity • Ferritin ... If no response HLH
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Screen for HLH ... HLH syndrome 5 ... #Pancytopenia #Workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... fever syndromes Clinical ... Fever is the main clinical ... hypersensitivity syndromes • HLH ... dehydrogenase • ↑ Ferritin
Causes of Approach to Altered Level of Consciousness - Workup Clinical Exam - Focal • Trauma •
Consciousness - Workup ... Clinical Exam ... Imaging Section Clinical ... Refer to Blood Work ... #diagnosis #workup
Primary Amenorrhea Differential Diagnosis Framework Workup: • β-HCG, TSH and PRL • Breast Tanner Staging • FSH,
Diagnosis Framework Workup ... Staging • FSH, LH
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