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management hematology differential symptoms autoimmune bronchiectasis chronic cll dermatology erythematosus gout hemophagocytic hlh leukemia leukostasis lupus lymphocytic lymphohistiocytosis lysis myopathy
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... effusion, Restrictive lung ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... organ damage • Treatment ... #TLS #diagnosis ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... microglobulin Treatment ... #workup #oncology ... #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... granulomas within the lungs ... Self-limiting, chronic but stable ... anterior/posterior MSK ... #Management #Signs
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... 12-24 Hours • Fever ... double contour sign ... +Radiographic signs ... #rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... Nasal polyps and signs ... in the adjacent lung ... of the affected lung ... mycobacteria Treatment
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... : Fever, joint pain ... : • Fever • Interstitial
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