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diagnosis management differential lupus sle systemic dermatology dermatomyositis symptoms vasculitis ana antibodies antimda5 antimda5dm antinuclear antinxp2 antinxp2dm arthritis chronic classification
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Rheumatoid Arthritis Summary ... Rheumatoid Nodules, Pulmonary ... Disease and ILD ... RA #diagnosis #rheumatology ... #signs #symptoms
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and progressive fibrosis ... : ILD (interstitial ... lung disease), ... Scleroderma #SSc #rheumatology ... symptoms #testing #workup
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Treatment: • Mild ... #SLE #Summary # ... diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management Summary ... • Immunologic Workup ... Evolution: Chronic disease ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Systemic lupus erythematosus ... Systemic lupus erythematosus ... , Interstitial Pulmonary ... Fibrosis, Multiple ... ANA #patterns #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... chest (in a V-sign ... violaceous macules and erythematous ... severity of the disease ... Dermatomyositis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... purpura: strong sign ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Systemic Lupus Erythematosus ... • Immunologic Workup ... Evolution: Chronic disease ... comparison #table #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Physical Exam/Signs ... cells can indicate disease ... Leukemia #diagnosis #workup ... #oncology #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
progressing GN • New pulmonary ... purpura: Strong sign ... ischemia • Skin: Erythematous ... MPO > PR3) • Pulmonary ... Differential #Diagnosis #Rheumatology
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