36 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and progressive fibrosis ... calcinosis • Pulmonary ... : ILD (interstitial ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... solid cancers • Systemic ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
- Differential Diagnosis ... , Sarcoidosis, Still's ... Psoriatic Arthritis, IBD-Associated ... #Differential #Diagnosis ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... episode (30%) Systemic ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #treatment
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Tissue Disease: • Systemic ... • Idiopathic pulmonary ... fibrosis (IPF), ... #diagnosis #differential ... #pulmonary #causes
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... skin disease, Pulmonary ... fibrosis Anti-centromere ... Autoantibodies #diagnosis ... #rheumatology
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... - Differential Diagnosis ... Pneumonitis • Treatment ... Chemotherapeutic Systemic ... lung #disease #pulmonary
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... ConnectiveTissueDiseases #ILD ... LungDisease #CTILD #Diagnosis ... Comparison #Table #Pulmonary ... #Rheumatology #
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... Classic triad of ILD ... /full triad at diagnosis ... after 2 years of treatment ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology