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diagnosis differential diseases druginduced interstitial syndrome activation algorithm amiodarone antinxp2 antinxp2dm boop comparison cop cryptogenic dermatology dermatomyositis dil hematology induced
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... Polymyositis-dermatomyositis, Lupus ... • Idiopathic pulmonary ... fibrosis (IPF), ... #causes
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... #treatment #management ... #rheumatology #
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... Interstitial Pneumonia - fibrosis ... leaking out of pulmonary ... Arthritis, Systemic Lupus ... #Diseases #ILD
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
Unknown • 6-7 cases ... Organizing Pneumonia Treatment ... Pneumonia #COP #BOOP #pulmonary ... #ILD #diagnosis ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... granulomas within the lungs ... symptoms are not caused ... Pulmonary: dyspnea ... skin (16-32%): lupus
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... starting amiodarone treatment ... Exclusion of other ILDs ... macrophages Treatment ... #diagnosis #management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Prognosis: Usually mild ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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