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diagnosis druginduced infections sle activation blastomycosis comparison dil erythematosus fungal fusarium hematology macrophage mas mycoses nephritis nephrology summary syndrome systemic
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... #treatment #management ... #rheumatology #
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... : • Mild disease ... Summary #diagnosis #rheumatology ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Prognosis: Usually mild ... constitutional symptoms • Treatment ... #DIL #rheumatology ... #diagnosis #treatment ... #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
Fever - Reticulin fibrosis ... including systemic lupus ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
Refractory FUO, Sino-pulmonary ... disease: • Optimal treatment ... isavuconazole) for mild ... Fusarium #Infections #infectiousdiseases ... #diagnosis #management
Blastomycosis Summary Pathogen: • Dimorphic fungus - Blastomyces dermatitidis or Blastomyces gilchristii. • The fungus lives
The Disease: • Pulmonary ... serum/urine Treatment ... : • Mild-moderate ... Blastomycosis #diagnosis #management ... #treatment #infectiousdiseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
host): • Chronic pulmonary ... symptoms • Rheumatologic ... Histoplasmosis Treatment ... ) #Mycoses #InfectiousDiseases ... Fungal #Diagnosis #Management
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