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hematology differential hemolytic management agglutinin algorithm cold cvid deficiency disease folate folicacid hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma mcv nonpalpable nutrition
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... • Bleeding • Hemolysis ... #MCV #Classification ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... #Diagnosis #causes ... #classification ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
nose, ears, or fingers ... symptoms - most common ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... • Bacterial endocarditis ... #Differential #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... cancers: Most common ... and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... ) Classification ... #classification
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
dietary intake - uncommon ... pregnant have hemolytic ... anemia, or psoriasis ... folate that can cause ... #differential #diagnosis
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