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diagnosis rheumatology erythematosus sle symptoms systemic causes vasculitis arteritis autoantibodies chronic classification dermatology gca giantcell management mimickers petechiae petechial physicalexam
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
), Depression, Fatigue ... Photosensitivity, Butterfly rash ... of hip (rare), Arthritis ... ) Blood (75%): Anemia ... erythematosus #signs
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
- Differential ... Neoplastic / Hematologic ... • Anemia • ... • Rheumatoid Arthritis ... Pulmonary Disease Neurologic
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... 69% - Malar rash ... - Hemolytic anemia ... autoantibodies #signs ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Clinical evidence of (fatigue ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... deficiency Work ... #Differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... • Fevers • Fatigue ... purpura: strong sign
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... subtle e.g. extreme fatigue ... very remarkable w/differential ... systemic complaints- anemia
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... : • Fevers • Fatigue ... purpura: Strong sign ... affects the skin, neurologic ... , mucositis • Rash
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