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hematology differential secondary systemic generalized leukemia myelodysplastic pruritus aplastic cll common cvid essential et gravis hemeonc hypogammaglobulinemia immunodeficiency immunology lymphocytic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... old, ~10,000 new cases ... cytopenias (usually anemia ... #MDS #Diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... (MDS) (normal or ... Hypocellular/Hypoplastic MDS ... #oncology #hematology ... #diagnosis #management
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
discoloration) • Chronic ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
and Primary Causes ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... Matthew Ho, MD ... #Algorithm #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... #diagnosis #management
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Oncology #Diagnosis
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