10 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... the peripheral blood ... purpura/hemolytic ... , Hematology 2012 ... , p 193 #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
nose, ears, or fingers ... Acrocyanosis (Cold-induced ... Diagnosis: • hemolytic ... sensitize red blood ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #hematology #testing
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Algorithm Spurious ... • Rheumatic disorders ... following EtOH induced ... thrombocytopenia ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Causes: - Drug induced ... DIC/TTP/HUS - Hemolytic ... #Differential #Diagnosis ... #nonpalpable #dermatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Mechanical valve induced ... Unstable hemoglobin disorders ... #differential #diagnosis
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... loss, hemolysis ... (BM) ablative disorders
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... hemostasis: - Thrombocytopenia ... Vasculitis - Collagen disorders ... #dermatology #physicalexam
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
: • Leukocyte reduced ... RBC • Volume Reduced ... purpura & severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... Neutropenia • Platelet Disorders ... Myelodysplastic #Syndromes #diagnosis