12 results
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
disease (10%) : SLE ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Butterfly rash, Vasculitis ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Clinical features of focal cortical brain lesions in a right-handed individual

Frontal, either:  
Intellectual impairment, 
Personality
Clinical features ... recognition #Cortex ... #Localization #Symptoms ... #Signs #Diagnosis ... #Neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Viral Infection Clinical ... nose, ears, or fingers ... anemia • Cold ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
pylori test (GI symptoms ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... Jorge Cortés @Jcortesizaguirr
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... affects the skin, neurologic ... • Progressive symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... = vasculitis vs ... systemic complaints- anemia ... #Symptoms #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia