11 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... - Differential Diagnosis ... capillary leak syndrome ... #Significance #MGUS ... #hematology #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... dermatoses #skin ... #Rash #oncology ... #cancer #MINTC ... #Mnemonic #dermatology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... the hematologic cancer ... IgM MGUS: • Serum ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... plasmacytoma, POEMs syndrome ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Leukemia cutis Diagnosis ... #diagnosis #dermatology ... #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... nose, ears, or fingers ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Hepatomegaly • Skin ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Gammopathy Include: • MGUS ... gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Tumor lysis syndrome ... lymphoid organs When Cancer ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis