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pathophysiology differential autoimmune clinical crest dermatomyositis diffuse lesions myelopathy myopathy myositis pm polymyositis pustular rash rheumatology scleroderma secondary syndrome systemicsclerosis
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
) • Hand paresthesias ... , fine finger dexterity ... #Myelopathy #diagnosis ... #signs #symptoms ... #msk
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
nodules under skin ... ) - Finger/hand ... and bushy - Finger ... pathophysiology #signs ... #symptoms #diagnosis
CREST Syndrome: Pathogenesis and Clinical Findings CALCINOSIS (BB-sized, hard nodules in fingers) RAYNAUD'S Phenomenon ESOPHAGEAL DYSMOTILITY SCLERODACTYLY (thickening and tightening
hard nodules in fingers ... tightening of skin ... TELANGIECTASIA (In face, hands ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... dorsum of the hands ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Irregular pustules on hands ... Burrows between fingers ... Secondary syphilis ... #Dermatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... ) • Shawl sign ... flexors, quadriceps, finger ... elevated < PM and DM ... • Mechanic's hands
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