7 results
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
hard nodules in fingers ... tightening of skin ... TELANGIECTASIA (In face, hands ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Diffuse Systemic Sclerosis (Scleroderma)
 - Pulmonary Fibrosis -> Crackles, Abnormal CXR
 - Pulmonary Hypertension, Right Heart
nodules under skin ... ) - Finger/hand ... and bushy - Finger ... pathophysiology #signs ... #symptoms #diagnosis
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... or the anterior chest ... #rheumatology #dermatology ... #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... dorsum of the hands ... -> Heliotrope Rash ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... #Diagnosis #Clinical ... #Photo #Dermatology
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
associated with signs ... soles, sides of fingers ... pruritus (e.g., fingers ... axillae, between fingers ... #diagnosis #skin
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... : • Gottron rash ... flexors, quadriceps, finger ... elevated < PM and DM ... • Mechanic's hands