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diagnosis hematology oncology causes syndrome activation algorithm behcet bruising chronic cll dermatology disease leukemia lymphocytic macrophage mas mds myelodysplasia myelodysplastic
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Autoimmune • ITP • SLE
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... Associated - SLE ... #Differential # ... #rheumatology #
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
) - SLE ( ... Acquired - Aplastic ... anaemia ... , SLE - Scurvy ... pediatrics #diagnosis #differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... infections/fevers • Thrombocytopenia ... anemia Treatment ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... with leukopenia, anemia ... , and thrombocytopenia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... • Neutropenia, anemia ... , thrombocytopenia ... Pure red cell aplasia ... microglobulin Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... • Aplastic Anemia ... IDUS) • Immune Thrombocytopenia ... blood count with differential ... Syndromes #diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
lesions, palpable purpura ... Behcet disease) Differential ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
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