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treatment differential syndrome comparison stills adultonset aosd blood cppd gout nephrology product reactions table activation adult algorithm approach arthritis autoimmune
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
onset - Mostly ... within one hour or longer ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... categories of joint disease ... -60 minutes or longer ... Joint #Pain #MSK #rheumatology ... #differential #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
intracellular contents ... Elevated Cr, Low calcium ... treatment (no calcium ... Syndrome #TLS #diagnosis ... #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... with established disease ... Avoid meds that ... #hematology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease Mild: • Trial of PPI • Trial
Severity of the Disease ... Concern for HES: • Hematology ... consult for evaluation ... • Additional diagnostic ... Gastroenteritis #Treatment #management
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... AdultOnset #Stills #Disease ... #AOSD #rheumatology ... #diagnosis #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... lasting two weeks or longer ... #rheumatology # ... management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... precipitates with calcium ... ankles, knees, fingers ... Gout #Comparison #rheumatology ... #Diagnosis
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