33 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... • Brushfield spots ... incurved fifth finger ... #Downs #Syndrome ... PhysicalExam #Features #Signs
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
PIP Involvement, Spares ... Tunnel, Sicca Syndrome ... Instability, Felty's Syndrome ... RA #diagnosis #rheumatology ... #signs #symptoms
Positive Hoffmann's sign (finger flexor reflex)

Flexion and adduction of the thumb and flexion of the index
Positive Hoffmann's sign ... (finger flexor ... #Hoffmanns #sign ... #orthopedics #neurology ... #sports
Wartenberg Sign in Ulnar Neuropathy

Abnormal abductor the fifth finger due to ulnar neuropathy ( weakness of
Wartenberg Sign ... abductor the fifth finger ... #Wartenberg #Sign ... #physicalexam #neurology ... #msk #sports #orthopedics
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Guillain Barre Syndrome ... sensory symptoms or signs ... nervous system signs ... except in Miller Fisher ... diagnosis #criteria #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... • Weakness: Starts ... death Miller Fisher ... #diagnosis #management ... #treatment #neurology
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
Well-localized, sharp, short ... well-localized, dull, longer ... regional pain syndrome ... Pain #Mechanisms #Neurology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... objective evidence of neurologic ... taper 3-7 days - Short ... sclerosis #diagnosis #management ... #neurology #treatment
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Clubbing of the Fingers ... nonuniform white spots ... Spots in the pattern ... seen in Reiter's syndrome ... Diagnosis #Clinical #Signs