68 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
Characteristic clinical ... manifestations of Down syndrome ... • Brushfield spots ... iris (pigmented spots ... #Downs #Syndrome
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... K-ATPase which imports ... - Refeeding Syndrome ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... • Weakness: Starts ... Treatment: • Plasmapheresis
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - ... Differential Diagnosis ... • Turner Syndrome ... Panhypopituitarism Treatment ... #ShortStature #Differential
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
CREST Syndrome: ... Pathogenesis and Clinical ... hard nodules in fingers ... MTPs) #CREST #Syndrome ... #Pathophysiology
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag Syndrome ... Purple #Urine #Bag #Syndrome ... #PUBS #pathophysiology ... #clinical #photo ... #differential #
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Pathogenesis and clinical ... =>Prader-Willi Syndrome ... fractures • Short ... #genetics #pathophysiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Diagnosis - Clinical ... Clinical DX: - ... stimulation - Single fiber
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
Diplopia TIER 1-CRITICAL ... , Orbital apex syndrome ... tumor, Miller-Fisher ... syndrome, Multiple ... mass #Diplopia #differential
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... lesions in the inner ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology