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diagnosis differential hematology iron msk pain pathophysiology rheumatology thrombosis venous anemia arthritis b12 cardiology clots cobalamin dermatology extremity joint leg
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Protein S deficiency ... Myeloproliferative disease ... Ischemic Liver, IBD ... Arterial Embolism ... coagulation and other causes
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Edema, Celiac disease ... (IBD, cancer) ... #Iron #Deficiency ... #nutrition
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Inflammation: IBD ... , Chronic disease ... #Causes #differential ... diagnosis #anemia #nutrition
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... PFO: paradoxical emboli ... artery aneurysm: Causes ... arterial clot, ... Lipoprotein a ↑ - IBD
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Stroke Volume / Arterial ... • Severe iron deficiency ... Arteriovenous fistula ... coronary heart disease ... Worse outcomes in CKD
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
necrosis) • VIT K deficiency ... Others: • Fat emboli ... • Cholesterol emboli ... • Septic emboli ... gangrenosum • Bacterial
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Legg-Calve-Perthes disease ... • Bursitis • IBD ... ulcers, Edema Arterial ... Vit B12, B6, Cu deficiency ... lower #extremity #msk
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... papillae of tongue), abd ... diarrhea related to IBD ... , celiac disease ... diagnosis #management #nutrition
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
weeks) Can Be Caused ... Rheumatologic Disease ... burgdorferi (Lyme disease ... Ankylosing Spondylitis, IBD ... Differential #Diagnosis #MSK
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