23 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... of Action Diuretics ... urearetics) 3) Loop ... Adenosine #Nephron #Pathophysiology
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
(B) Treatment algorithm ... Total loop diuretic ... maximal dose for IV loop ... following a single loop ... #CHF #Algorithm
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... shown in Panel C, diuretics ... #Pathophysiology
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Spironolactone Loop ... Diuretics Thiazides ... Acetazolamide #Diuretics ... #pharmacology #pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
the Nephron - Diuretics ... Acetazolamide 2) Osmotic Diuretics ... mannitol) 3) Loop ... Diuretics (e.g. ... spironolactone) #Pathophysiology
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
a Mechanism of Diuretic ... high doses of loop ... diuretics are used ... #Pathophysiology
Hyponatremia Treatment Algorithm

CHF, Cirrhosis - Fluid restriction
SIADH - Fluid restriction
 - Consider salt tablets if etiology
Hyponatremia Treatment Algorithm ... consider adding loop ... diuretic Reset ... -> free water diuresis ... Hyponatremia #Treatment #Algorithm
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Adenoma • Remote Diuretics ... - Loop or Thiazides ... Hyperaldosteronism • Recent Diuretics ... - Loop or Thiazides ... metabolic #alkalosis #algorithm
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Differential Diagnosis Algorithm ... Urine Mg > 10g • Loop ... Diuretics • Hypercalcemia-PTH ... syndrome • Thiazide Diuretics ... Differential #Diagnosis #Algorithm
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... Differential #Diagnosis #Algorithm