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Antibiotic Tissue Penetration Blood Brain Barrier: Penicilins (IV), 3rd & 4th generation Cephalosporins (IV), Meropenem, TMP-SMX, Metronidazole,
Metronidazole, Linezolid, Fluoroquinolones ... Prostate: Fluoroquinolones ... Beta-lactams, Fluoroquinolones ... Ceftriaxone Bone: Fluoroquinolones
Fluoroquinolones - Antibiotics Class Overview Mechanism: DNA Gyrase and Topoisomerase inhibitors bactericidal Side effects: QT prolongation
Fluoroquinolones ... Fluoroquinolones ... - Fluoroquinolones ... resistance) - All fluoroquinolones ... - All fluoroquinolones
CAP, HCAP, HAP and VAP - Diagnosis and Treatment HCAP & CAP – those presenting to the
CAP, HCAP, HAP and ... VAP - Diagnosis ... & CAP – those presenting ... twitter.com/foamid #CAP ... #HCAP #HAP #VAP
Outpatient Treatment of with Community-Acquired Pneumonia (CAP) No comorbidities or risk factors for MRSA or Pseudomonas aeruginosa:
Community-Acquired Pneumonia (CAP ... with respiratory fluoroquinolone ... IDSA #Outpatient #CAP
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS Preventing Bacterial Enteric Illness: • Antimicrobial
prophylaxis with fluoroquinolones ... or rifaximin can ... alternative to fluoroquinolone
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
Telithromycin • Fluoroquinolones ... Patients with MuSK-MG ... muscle-specificreceptortyrosinekinase #AChR #MuSK
Antibiotics and CNS Diffusion 1. Drugs with good CNS diffusion: - Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole 2. Drugs
diffusion: - Fluoroquinolones
Campylobacter Clinical • Fever • Abdominal pain • Diarrhea (bloody stools) • Vomiting
severe disease • Fluoroquinolones
Antibiotic Classification by Mechanism of Action Cell Wall Synthesis: Penicillins Cephalosporins Carbapenems Monobactams Beta-lactamase inhibitors Glycopeptides Protein
Topoisomerases: Fluorquinolones
Antibiotics used for the Treatment of Pseudomonas Aeruginosa in Adults • Penicillin-beta-lactamase combinations: Piperacillin-tazobactam, Ticarcillin-clavulanate •
Aztreonam • Fluoroquinolones
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