13 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... , Folate Deficiency ... MatthewHoMD #Macrocytic ... #Anemia #differential
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... but undiagnosed, folate ... #Macrocytosis #Macrocytic ... #Anemia #VitaminB12 ... #Folate #FolicAcid
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... Framework by MCV Microcytic ... Sideroblastic anemia ... Infections Macrocytic ... Megaloblastic: Folate
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Deficiencies After Gastric ... cardiomyopathy) • Folate ... - Macrocytic anemia ... Vitamin B12 - Macrocytic ... #Deficiencies #Gastric
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Morphology Atlas • Microcytic ... Iron-deficiency anemia ... Sideroblastic anemia ... Lead poisoning • Macrocytic ... diseases, Bleeding gastric
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... MCV - <80fL - "Microcytic ... thalassemia • Anemia ... MCV - >96fL - "Macrocytic ... B12 deficiency, Folate
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Drugs Oval Macrocytes ... Neutrophils - Low RBC Folate ... Rule out B12 and Folate ... Liver Disease #Macrocytic
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... (sometimes) Macrocytic ... Vitamin B12 or Folate ... iron deficiency anemia ... Autoimmune hemolytic anemia
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
malabsorption (d/t reduced gastric ... : • Worsening macrocytic ... anemia, yellow ... wt loss • If anemia ... surgeries (bariatric, gastric
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
of pernicious anemia ... #Pathophysiology ... #NitrousOxide #VitaminB12