44 results
diagnosis oncology syndrome treatment dermatology disease vasculitis classification hemeonc hemophagocytic hlh lymphohistiocytosis thrombocytopenia anemia causes chronic cll cryoglobulinemia hodgkins leukemia
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
Non-HCV infectious ... Specific anti-infectious ... related to HBV infection ... absence of anti-infectious ... Cryoglobulinemia #Vasculitis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... community-acquired infections ... hypogammaglobulinemia #immunology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... Still disease, Infection ... Etiological+++: Anti-infectious ... treatment #summary #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Disease #diagnosis #management ... #treatment #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post infectious ... hemolytic #anemia #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... Autoimmune diseases • Clinical ... Etiology: - Infections ... involvement Differential ... #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Idiopathic • Infections ... : HCV infection, ... HBV infection, ... HIV infection ... classification #rheumatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... predictive of a serious infection ... overlook severe infections ... superior indicator of infection ... neutrophil #WBC #CBC #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... procedures - Infection ... (CVID, WAS), (neurologic ... or if a primary hematologic ... Causes #Workup #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... Framework The DDx ... • Parasitic infections ... #Tryptase #Differential ... #Diagnosis #hematology
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