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hepatology algorithm phosphatase workup aflp biliary cancer cholangitis cholestatic cirrhosis disorders elevation emergencies enzymes fatty gap globulin hepatitis hepatocellular hepatorenal
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
) - Causes of Hepatocellular ... + ULN ALT) / (alkaline ... Transaminitis #diagnosis ... #differential # ... hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... Intestine - Other causes ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... Most cases diagnosed ... • recurrent fractures ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Vascular Causes ... of Acute Liver
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral ... Pregnancy #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... (CVID, WAS), (neurologic ... not required in all ... #Diagnosis #Causes
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework ... HEMATOLOGIC ... of breath • Neurologic ... Hyperuricemia • Acute
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... PBC Labs: • Alkaline ... obstruction • ALP ... bile ducts Differential ... #workup #hepatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
hepatitis, or acute ... • Caused by splanchnic ... evaluation essential in all ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... characteristic feature ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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