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diagnosis hematology causes algorithm bruising purpura bleeding dermatology nonpalpable palpable pathophysiology petechiae anemia arterial blanching bruise ecchymosis embolism extravascular extrinsic
Simplified Coagulation Cascade and Differential Diagnosis #Coagulation #Cascade #Differential #Diagnosis #Intrinsic #Extrinsic #Pathway #Hematology
Simplified Coagulation ... Cascade and Differential ... Diagnosis #Coagulation ... #Cascade #Differential
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
and Bruising - Differential ... Quantitative (Thrombocytopenia ... Qualitative • Coagulation ... Bleeding #Bruising #Differential
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Post-Partum Hemorrhage - Differential ... • Idiopathic thrombocytopenic ... intravascular coagulation ... (DIC) • Anti-coagulation ... Hemorrhage #PPH #Differential
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Diagnosis Algorithm Thrombocytopenia ... • Vasculitis Coagulation ... deficiencies Coagulation ... Bleeding #Bruising #Differential
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... • Thrombotic Thrombocytopenic ... Metabolism-mediated TMA - Coagulation-mediated ... TMA #hematology #differential
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura - Differential ... → Palpable • Thrombocytopenia ... HIT, ITP/HUS), Coagulation ... palpable #Causes #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... vascular disorders, coagulation ... inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... Vasculopathy #Purpura #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes #differential
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
individuals with thrombocytopenia ... are typical of coagulation ... Measurement of coagulation ... VWF:RCo/VWF:Ag (differentiate ... Bruise #ecchymosis #thrombocytopenia
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... hemostasis: - Thrombocytopenia ... Complete blood count coagulation ... Petechiae #Rash #Differential
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