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diagnosis differential management pharmacology clinical algorithm causes antibiotics acidosis pathophysiology table treatment comparison criticalcare nephrology radiology workup classification microbiology gastroenterology
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
Lactic Acidosis ... Diagnosis Type A Lactic ... , Epinephrine, Fructose ... , Isoniazid, Lactate-based ... #TypeA #TypeB #lactate
Lactic Acidosis Classification - Type A vs Type B Type A Lactic Acidosis: Sepsis, Ischemic bowel, Hemorrhagic
Lactic Acidosis ... Type B Type A Lactic ... Cardiogenic shock Type B Lactic ... Short bowel (D-lactate ... transcriptases, Linezolid #Lactic
Lactic Acidosis - Overview and Pathophysiology Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis ... Pathophysiology Lactic ... Lactate is the conjugate ... base of lactic ... as an arterial lactate
Lactic acid was first found & described in sour milk by Karl Wilhelm Scheele in 1780.
Lactic acid was ... occurrence of lactic ... Lactic acid is essentially ... equilibrium with lactate ... Thus, lactate is
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... contribute to lactic ... Elevation Type A Lactic ... Methemoglobinemia Type B Lactic ... #Lactic #Acidosis
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... DKA, Alcoholic lactic ... with negative lactate ... sugars into D-Lactate ... @nickmmark #Lactic
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK Glycols - ethylene and propylene glycol Oxoproline
acetaminophen use L-lactate ... metabolism D-lactate ... toxicity causes lactic
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Lactated Ringers ... mEq/L • Sodium lactate ... pH of 4-7.5 Lactated ... mEq • Sodium Lactate ... NOT lactic acid
Food carbohydrates Starch Polysaccharides Salivary amylase G) Pancreatic amylase Lactose Maltose Lumen Lactase Maltase O Sucrase Saccharose Disaccharides Nat cotransport carrier Villus epithelial cell Galactose Glucose Glucose Glucose Glucose Fructose Galactose Na*- and energy- dependent absorption Glucose Facilitated diffusion #Fructose Monosaccharides Energy dependent Blood capillary Na+
Pancreatic amylase Lactose ... Maltose Lumen Lactase ... Glucose Glucose Fructose ... Facilitated diffusion #Fructose
Lactulose: Mechanism of Action in Hepatic Encephalopathy Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose → ↑ Lactic ... Acid, Acetic Acid
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