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diagnosis hepatology differential liver lfts transaminitis hepatitis abnormal aflp alkaline causes chemistry comparison disease hellp hepatocellular icp injury interpretation liverenzymes
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs) Elevation ... ≥ 3x ULN Cholestatic ... pattern ≤2: Cholestatic ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Hepatocellular and Cholestatic ... elevation > Alk ... R ≤ 2 = Cholestatic ... AnnKumfer #Liver #Enzymes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... of cholestatic ... or amyloid: • Elevation ... Source of Liver Enzyme ... Elevation: •
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... ALP: - Enzymes ... of Intrahepatic cholestasis ... - Pruritis - Cholestasis ... #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... Source of Liver Enzyme ... Elevation: • ... differential #diagnosis #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Severe ALT > 15x ... • Others • Cholestatic ... Differential #Diagnosis #Algorithm
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Intrahepatic Cholestasis ... to 10-20-fold elevation ... Histology: Normal-mild cholestasis ... Elevated Liver enzymes ... to 10-20-fold elevation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... the magnitude of enzyme ... elevation and clinical ... LFTs #Abnormal #Algorithm ... Hepatology #Liver #Enzymes
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