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diagnosis differential hepatology liver lfts hepatitis transaminitis interpretation management pediatrics peds abnormal aih aki alkaline autoimmune causes chemistry child creactiveprotein
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs) Elevation ... Hepatocellular injury ... 2: Cholestatic injury ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... Interstitial Lung Disease ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... of cholestatic disease ... or amyloid: • Elevation ... Alcoholic liver disease ... of Liver Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Venoocclusive disease ... Bilirubin - +/- elevation ... of Liver Enzyme Elevation ... differential #diagnosis #algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Other causes of elevation ... elevation DDX of ... #Diagnosis #Algorithm
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
mg/L: Moderate elevation ... other autoimmune diseases ... Recent injury or ... or inflammatory disease ... and diabetes can all
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
increase in AST/ALT ... compared with AST/ALT ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... Diagnosis #hepatology #algorithm
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... alcohol-related liver disease ... LFTs #Abnormal #Algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Electrical injury ... 5X ULN • AST/ALT ... Elevation 4:1 ratio ... AST declines > ALT ... of underlying disease
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
• Legionnaires disease ... injuries Hepatic Injury ... Hepatocellular Injury ... Idiosyncratic LDH Elevation ... or particular disease
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