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diagnosis differential hematology causes aafp approach classification dm2 false hba1c hgba1c homocysteine increase laboratory macrocytic macrocytosis mma nutrition reduction thrombocytopenia
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False Elevation ... HbA1c == False Elevation ... Iron, B-12, or folate ... deficiency • ... • Hemolytic anemia
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... also causes an elevation ... but undiagnosed, folate ... #VitaminB12 #Folate ... #FolicAcid #MMA
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... have hemolytic anemia ... deficiency are ... anticonvulsants lead to increase ... #deficiency #FolicAcid
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Reticulocytes • Iron Deficiency ... • B12/Folate ... Deficiency • Aplastic ... Differential #Diagnosis #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Decreased Megakaryopoiesis ... • Aplastic Anemia ... • Folate Deficiency ... • Folate Antagonist
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