6 results
diagnosis differential causes workup approach classification deficiency dm2 false folicacid hba1c hgba1c laboratory normocytic nutrition reduction testing thromboticthrombocytopenicpurpura ttp
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Iron, B-12, or folate ... Reduction == Increase ... blood loss • Hemolytic ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Decreased WBCs ... - Decreased/NormaI ... Infiltration - Increased ... Bleed • Hemolysis ... #Causes #Hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... pregnant have hemolytic ... anemia, or psoriasis ... anticonvulsants lead to increase ... differential #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... combination of: Decreased ... Deficiency • B12/Folate ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... without platelet decrease ... #Anemia #Differential ... #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... result in severe anemia ... anemia Indirect ... Mild-to-moderate elevation ... Diagnosis #Workup #Hematology
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