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diagnosis hepatology differential lfts bilirubin chemistry transaminitis alkphos direct gastroenterology hepatitis hyperbilirubinemia injury interpretation laboratory metabolism pathophysiology rvalue tests
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Approach to Conjugated ... Differential Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... Differential #Diagnosis #Algorithm
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... hepatocyte - Elevation ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... Laboratory #Metabolism #ASTALT
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... or amyloid: • Elevation ... normal AST/ALT AST ... Enzyme Elevation ... blood cells Unconjugated
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... be abnormal AST ... injury: ~ 1 Unconjugated ... Enzyme Elevation
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