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diagnosis hepatology differential lfts hepatitis transaminitis alkaline injury interpretation laboratory management phosphatase abnormal aflp aih antimda5 antimda5dm autoimmune biliary causes
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... Interstitial Lung Disease ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Diagnosis #Algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... of cholestatic disease ... or amyloid: • Elevation ... disease: > 2 ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Venoocclusive disease ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... disease; AST, aspartate ... disease; T2DM, ... LFTs #Abnormal #Algorithm
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... to 10-20-fold elevation ... to 10-20-fold elevation ... of Pregnancy (AFLP ... #Disease #Pregnancy
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Severe ALT > 15x ... • Cholestatic disease ... Differential #Diagnosis #Algorithm
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
synthesized by the liver ... mg/L: Moderate elevation ... other autoimmune diseases ... or inflammatory disease ... and diabetes can all
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
increase in AST/ALT ... compared with AST/ALT ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... Diagnosis #hepatology #algorithm
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